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Qualifying conditions

What qualifies for a medical card?

Every state defines its own list — and a growing number let physicians certify any condition they believe cannabis can help. Pick a condition for specifics.

Chronic Pain

Chronic pain is the single most common reason patients seek a medical marijuana card in the United States, and it is an explicitly listed qualifying condition in the majority of state programs.

Explicitly listed in 33 states

Anxiety

Anxiety disorders are an explicitly listed qualifying condition in a handful of states — including Pennsylvania, New Jersey, and New Hampshire — and can qualify under physician-discretion rules in many others.

Explicitly listed in 3 states

PTSD

Post-traumatic stress disorder is one of the most widely accepted qualifying conditions in the country — it appears on nearly every state's list.

Explicitly listed in 33 states

Insomnia & Sleep Disorders

Sleep problems are a leading reason patients seek medical cannabis. A few states list sleep disorders directly, and many more allow them under physician discretion or as symptoms of listed conditions.

Explicitly listed in 1 state

Cancer

Cancer is a qualifying condition in effectively every medical marijuana program in the country, covering both the disease and treatment side effects.

Explicitly listed in 34 states

Epilepsy & Seizure Disorders

Epilepsy and seizure disorders appear on every state qualifying-conditions list, and were the original driver of many early medical cannabis laws.

Explicitly listed in 31 states

Multiple Sclerosis

Multiple sclerosis and the muscle spasticity it causes are listed qualifying conditions in nearly every state program.

Explicitly listed in 32 states

Crohn's Disease & IBD

Crohn's disease — and inflammatory bowel disease more broadly — is a listed qualifying condition in the large majority of state programs.

Explicitly listed in 28 states

Glaucoma

Glaucoma is one of the oldest listed qualifying conditions, appearing on nearly every state list.

Explicitly listed in 27 states

Migraines

Intractable migraines are explicitly listed in a few states (including Missouri and California) and qualify under physician discretion or chronic-pain provisions in many more.

Explicitly listed in 2 states

Arthritis

Arthritis is explicitly listed in several states (including Michigan, California, and Arkansas for severe cases) and commonly qualifies under chronic-pain provisions elsewhere.

Explicitly listed in 3 states

Depression

Depression is explicitly listed in Alabama and qualifies under broad psychiatric or physician-discretion provisions in states like Missouri, New York, Virginia, and Oklahoma.

Explicitly listed in 2 states

Autism Spectrum Disorder

Autism spectrum disorder appears on a growing number of state qualifying lists — including Alabama, Colorado, Georgia, Michigan, Minnesota, and Texas — driven largely by families seeking help with severe irritability, self-injury, and sleep disruption.

Explicitly listed in 13 states

Parkinson's Disease

Parkinson's disease is listed in most state programs — Florida, Georgia, Illinois, Kentucky, Mississippi, Missouri, New Mexico, West Virginia among them — though the evidence picture deserves the honest version.

Explicitly listed in 14 states

HIV/AIDS

HIV/AIDS appears on virtually every state qualifying list — a legacy of cannabis medicine's origins in the AIDS crisis, when appetite stimulation was the first widely recognized therapeutic use.

Explicitly listed in 31 states

ALS (Lou Gehrig's Disease)

ALS appears on nearly every state qualifying list, and many states fast-track or extend allowances for ALS patients given the disease's trajectory.

Explicitly listed in 21 states

Tourette Syndrome

Tourette syndrome is listed in a meaningful set of states — Alabama, Arkansas, Minnesota, Missouri, Ohio among them — and carries one of the more interesting small-trial records in cannabis medicine.

Explicitly listed in 3 states

Sickle Cell Disease

Sickle cell disease is explicitly listed in Alabama, Georgia, Kentucky, Mississippi, Ohio, Pennsylvania, and West Virginia — recognition of a brutal chronic-pain condition that disproportionately affects Black patients historically undertreated for pain.

Explicitly listed in 7 states

Huntington's Disease

Huntington's disease appears on several state lists — Missouri, Mississippi, New Mexico, West Virginia among them — for a condition with few good symptomatic options.

Explicitly listed in 3 states

Opioid Use Disorder

Pennsylvania lists opioid use disorder as a qualifying condition — a deliberate harm-reduction experiment — and several discretion states permit certification on similar reasoning. This page is more caveat than promotion, on purpose.

Explicitly listed in 1 state

Traumatic Brain Injury

Traumatic brain injury entered several qualifying lists recently — Texas added it in HB 46 (2025), and Ohio and Pennsylvania list it — reflecting demand from veterans and accident survivors managing the long tail of head injury.

Explicitly listed in 2 states

Hepatitis C

Hepatitis C remains on many state lists — Alaska, Arizona, Massachusetts, New Hampshire, Rhode Island, Washington among them — largely as a legacy of the interferon treatment era.

Explicitly listed in 8 states

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